This Just In: The Cast of A Million Little Things Is Ready to Make You Weep

Best known for playing Detective Nick Burkhardt in NBC's Grimm, David Giuntoli will star in the show as Eddie Saville, a former front man of a local band turned music teacher and stay-at-home dad who, though he loves being a dad, wonders what life would be like if he hadn't become a family man.

Ron Livingston, who played Captain Lewis Nixon in the 2001 miniseries Band of Brothers (but is probably best known for starring in the iconic comedy Office Space), will play Jon Dixon, a real estate titan who unexpectedly decides to take his own life.

Romany Malco — also known as Conrad Shepard from Showtime's Weeds — will appear in the show as Rome Howard, a commercial director with a seemingly perfect life who wishes he was doing something more meaningful.

Best known for starring in USA's Psych as Shawn Spencer, James Roday rounds out the foursome as Gary Mendez, a breast cancer survivor who just found out that his cancer is back (and who makes a habit of regularly picking up new ladies from his breast cancer support group).

Allison Miller, who is best known for playing Michelle Benjamin on the NBC series Kings, is set to play Maggie Bloom, a therapist who Gary meets (and subsequently begins a romantic relationship with) from his cancer support group.

Christina Moses, who played Jana Mayfield on The CW's Containment and Keelin on The CW's The Originals, will appear as Regina Howard, Rome's wife and a chef who wants to open her own restaurant.

Spanish actress and writer Christina Ochoa will play Ashley Morales, Jon's assistant who may best understand what compelled him to commit suicide.

French actress Stéphanie Szostak is set to play Delilah Dixon, Jon's widow.

Lizzy Greene, who played Dawn Harper in Nickelodeon's Nicky, Ricky, Dicky & Dawn, will appear as Sophie Dixon, Jon and Delilah's moody, gothic 16-year-old daughter.

American-Canadian actress Grace Park — also known as Officer Kono Kalakaua from the CBS series Hawaii Five-0 — will play Katherine Kim, Eddie's wife, who is juggling her law career, her failing marriage, and parenting her and Eddie's son, Theo.