At the end of Avengers: Infinity War [1], the few Avengers left standing [2] face worldwide — and personal — devastation. Their entire objective has been to stop Thanos's mad mission [3] and defeat him before he collects all six Infinity Stones [4] needed to complete the Infinity Gauntlet [5]. Of course, things don't go to plan, and Thanos ends up following through with his fatal snap, turning half of the universe to dust [6]. With his ultimate mission complete, Thanos seemingly disappears, leaving behind a lot of pain and confusion [7].
Now, we don't know where everyone who was dusted [8] has gone — though we have our suspicions [9] — but we have a fairly good idea of where Thanos disappears to after his work is done. The last time we see Thanos, he's on a lush, beautiful planet [10] in a hut. He limps to the entrance of the hut and sits down, gazing out into the sunset. Once seated, a small smile graces his face. He's genuinely at peace for the first time, because, as the Russo brothers explained to Complex magazine [11], "Once he puts his armor down in that movie he becomes like a holy warrior and this is his resting place for him."
Image Source: Marvel [12]
We don't exactly know what planet Thanos retires to (they never give it a name in the comics), but in the first trailer [13] for Avengers: Endgame [14], we see that he has quite literally hung up his suit of armor. The big man walks though a field, his arm — seemingly battered and still wearing the remains of the Infinity Gauntlet — brushing through the plants as he strides along. Whatever planet he's on looks incredibly tranquil, which we guess he needs after doing all that traumatizing work [15].
Thanos retiring to a planet completely on his own is similar to what he does in the Infinity Gauntlet comic. In that story, he retreats to a planet where he can live in solitude after faking his death to avoid defeat. In the comics, Thanos lives peacefully as a farmer (until he gets up to no good again), but we're pretty sure the Avengers aren't going to let him live out [16] that particular fantasy in Endgame.