Jolex begin as close friends, bonding over their troubled youth at Dr. Bailey's wedding. They finally become a couple after Heather's death, but later face rough roads ahead, especially following his father's arrival in Seattle. He asks her to marry her, to which she declines at first. Alex then finds Jo and Andrew in a compromising position, which leads to him beating up the latter and getting served with assault charges. Shortly after they get back together, Jo pops the big question, lining their home with candles. And then they get married (though only after hooking up in a barn that had a dead guy in it) despite a series of wedding mishaps. Cheers to the happy couple!