Weisz tops our list based on her role as Evelyn Carnahan, the librarian-turned-archaeologist in The Mummy and The Mummy Returns. Those movies show she's mastered the subtle nuances of the comic adventure story. Plus, her Oscar and Golden Globe-winning work in The Constant Gardner is evidence she can pull our heartstrings.
Some may argue her recent commitment to dramatic films like The Light Between Oceans puts her outside the casting net for Summer blockbusters, but we believe her experience on both sides of the emotional spectrum would give Indy the gravitas and levity required of a professor-turned-whip-cracking adventurer. Let's hope this mother-to-be loves leather jackets and fedoras as much as we do.