Saddest Grey's Anatomy Breakups
10 Grey's Anatomy Breakups That Destroyed Our Fragile Hearts
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Completely disarming McDreamy, Meredith delivers her iconic "pick me, choose me, love me" speech, begging Derek to sign his divorce papers and stay with her. She asks him to meet her at Joe's, and he's a no-show. Poor Mer lays her heart out on the table only to have Derek be late and basically choose Addison in the next episode without saying anything to Meredith (at least non-professionally, as they do work a case together).