Amy Schumer didn't have an easy journey to motherhood with son Gene [1], who is now 15 months old, so it's understandable that – despite resuming in vitro fertilization treatments earlier this year – she's having second thoughts about future pregnancies.

The comedian completed an egg-retrieval process back in January [2] and the next month revealed that she and husband Chris Fischer secured at least one embryo, but in a preview for an episode of Sunday Today With Willie Geist, she is reconsidering her plans.

"We did IVF and IVF was really tough on me," she said. "I don't think I could ever do IVF again."

Between that and her nine-month struggle with hyperemesis gravidarum, a severe pregnancy complication that comes with severe nausea and vomiting, she seems ready to accept that she won't conceive or carry any potential future children.

"I decided that I can't be pregnant ever again," she said. "We thought about a surrogate, but I think we're going to hold off for right now."

Of course, whether they grow their family or not, she and Chris feel complete with Gene right now.

"Life is so much more beautiful," she said. "He's the best thing in my life."