Another locale with dry air, Scottsdale earned its spot as the third-highest city in Botox sales. "In colder parts of the country during the Winter when people stay in and hibernate, there is a tendency to have treatments done for specific events, like a New Year's Eve party," Dr. Youn said. "This is contrasted with warmer areas, where people are being seen year-round and may feel more pressure and need to look their best all the time."