Indiana Jones is a character with an interesting aesthetic dichotomy in that the professor must look convincingly nerdy while ensconced in academia and suitably athletic in the jungle. Beckinsale is one of the few actors on this list who can pull off both looks and deliver believable butt-kicking stunts. And with her work in Van Helsing and the Underworld series, we know she'd be staunch opponent for the Mola Ram or any other duplicitous foes.