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Murder House — Constance Langdon

In the first season, AHS: Murder House, Lange played Constance Langdon, the next-door neighbour to the infamous Murder House. She seemingly befriends the Harmon family when they move in, but she keeps to herself her knowledge of all the creepy happenings that the house has seen over the years, including several horrific murders. Constance has three children, all of whom end up dead before the season ends, though her son Tate, played by Evan Peters, still lurks around the Harmons' house in some human-like form. He knocks up Vivien Harmon (Connie Britton), though she thinks it's her husband, and she gives birth to his baby, whom Constance keeps as her own. That baby, now grown, is set to play an important role in Apocalypse, leading us to believe Constance may be back as well!

Image Source: Everett Collection