Before his marrying Izzie, Alex helps a graduating valedictorian named Becca (Amy Gumenick) who gets into a car accident with her friends. It's a pretty sad storyline since she ends up being the only person who lives of all her friends. Before she goes into surgery, Alex has her recite her speech to calm her down. Later on, he incorporates some of the lines into his wedding vows to Izzie, telling his wife that it's "the day his life begins."