The dark remix of the 1995 hip-hop song blew up after the trailer for the movie first came out, and plays a few times in the movie. The most memorable time it plays is during the first act of the film, when the Wilson family are driving around Santa Cruz. "It's about drugs," Zora tells her younger brother, before her father, Gabe (Winston Duke) cuts her off, proclaiming, "It's not about drugs. Don't do drugs."
So, um, yeah it is about drugs. Specifically, the hook references someone throwing down half for a dime bag of pot. But for Peele, the song held a different meaning in the context of the film:
"That song, it came pretty simple, I'm making a movie in Northern California, that's a bay area hip-hop classic and I wanted to explore this very relatable journey of being a parent [and] maybe some of the songs you listened to back in the day aren't appropriate for your kids," he told EW. "So that was one level, and another part was, I love songs that have a great feeling but also have a haunting element to them and I feel like the beat in that song has this inherent cryptic energy, almost reminiscent of the Nightmare on Elm Street soundtrack . . . also, it's just a dope track."