The eighth season of Grey's Anatomy ends with a literal bang, as the plane intended to take a group of doctors to assist in a surgery in Boise, ID, crashes in the woods and the survivors have to fight for their lives. It's a harrowing episode made that much worse by the occasional cuts back to the hospital, where no one has even noticed they're missing. This episode ultimately claims the lives of Lexie Grey and Mark Sloan, along with Arizona Robbins's leg, Derek Shepherd's hand, and Cristina Yang's mental health. It also has multiple-season-spanning repercussions, as the surviving doctors eventually wind up suing, bankrupting, and ultimately buying the hospital, leading to its renaming as Grey Sloan Memorial.