As with all of the original X-Men films, whether or not the events of X2 still take place in a post-Days of Future Past world is murky at best. The conflict in this film revolves around William Stryker, who is definitely still around in this new timeline but has been at least slightly altered by the events of Days of Future Past and Apocalypse. Whether or not he still invades Xavier's school hoping to get his hands on Cerebro is anyone's guess.