The namesake of this family was Tommy Lucchese, who immigrated to East Harlem from Italy in the 1910s and partnered up with organised crime groups in the area. He formed a gang with Charles "Lucky" Luciano and later went into the bootlegging business. He then allied with Tomasso Gagliano during a 1930 gang war which resulted in the formation of the Mafia Commission overseen by the five families. Lucchese became a boss in 1951, controlling unions in the clothes manufacturing, food distribution, airport, construction, and newspaper industries. The family also influenced local Teamster unions in New York and New Jersey. In May 2017, 19 members were arrested for racketeering and murder.
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