Netflix rewrites the character of Ana to give her a more prominent role in the live-action series. In the original, she's the owner of a convenience store on Mars and is a friend of Spike and Julia's. During the season finale, she gets shot after refusing to reveal Spike and Julia's whereabouts to a group of men from the Red Dragon Crime Syndicate.
In the Netflix version, Ana owns a jazz club that also serves as a hub for the criminal underworld. Ana also meets with Julia several times at the club to give her advice about Vicious.