"The most important thing to do is to get connected," Dr. Harrison said, and the science backs it up. According to a recent study, social connection is the most effective way to prevent depression as an adult. More specifically, confiding in others and visiting with friends and family were both important factors. Physically being with other people is not an option for many of us right now, so look for other ways to connect. Schedule Zoom calls with your friends and family, text your friends regularly, call up people you love when you're feeling down, or even write letters so you have something to look forward to.