"Moleskin makes a barrier between the skin and the sandal," Dr. Jaliman said. We're not talking about the trendy notebook — this is a woven cotton adhesive ($23). According to Dr. Jaliman, moleskin works well because "it is a very soft, padded material." You can cut and apply the patch over any problem areas you think might chafe, such as a sensitive part of your skin or the area on your foot that's right underneath an irritating shoe strap.