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Slide 6 of 20

Milo Ventimiglia and Hayden Panettiere

Hayden and Milo met on the set of Heroes in 2016, where they played niece and uncle — though that didn't deter some fans from shipping the pair. The two dated from 2007 to 2009, and they remained on the show until the end of the fourth and final season in 2010.

Following the experience, Milo told Mr. Porter in September 2017 that he would "never again" date a costar. "There are things that happen to you in your life that shape who you are," he added. "Everything I've been through from jobs to friendships to partnerships — everything has built me to who I am. You learn from it. You learn a better way of doing things. It wasn't until my mid to late twenties that the job wears on you, relationships wear on you. But I wouldn't change a thing. When you get knocked over the head in life, it builds your perspective."