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Slide 15 of 20

Dave Annable and Emily VanCamp

Jennifer and Michael aren't the only onscreen siblings who fell in love. Dave and Emily started dating after meeting on the set of Brothers & Sisters in 2006, where they played half-siblings Justin and Rebecca. Their chemistry was so palpable that a plot twist was added into the storyline where the two found out they weren't actually related and could date. Though the actors remained on the series until 2011, their real-life romance only lasted until 2008.

Neither actor has publicly spoken about their experience working together post-split, though in May 2012, Emily alluded to a past relationship that didn't end well during an interview with Lucky, saying "every young woman needs to have one boyfriend who disappoints her, who really breaks her heart" in order to know what true love is.

Image Source: Getty / John Shearer