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Kaley Cuoco

Kaley Cuoco, who plays sexy girl-next-door Penny, will be taking her talents to voice acting after the conclusion of The Big Bang Theory, voicing Harley Quinn and serving as executive producer in the animated series of the same name, debuting on the DC Universe streaming service in October. She'll also star in and produce the television adaptation of Chris Bohjalian's thriller novel The Flight Attendant, which tells the story of a woman who wakes up next to a dead body with no idea how she — or the body — got there.

As far as seeing Penny in a spin-off series, Cuoco revealed to Entertainment Tonight that the only person she would say yes to would be TBBT series creator and executive producer Chuck Lorre. " . . . if Chuck came and said let's do it, I'd say yes," she explained. "Other than that, I don't see a spin-off for myself. But I don't like to say no to Chuck. So if he wanted it, I'm in."