Lily Rabe reprises her role as Sister Mary Eunice in Freak Show, but only appears in one episode. Prior to the happenings of Asylum, Mary Eunice encounters Pepper (Naomi Grossman) for the first time in 1962. When Pepper is framed for her niece's murder, she is brought to Briarcliff, where Mary Eunice assigns her to work in the asylum's library.