Beginning her career in modelling, Appleton began acting in 2017 with her first role in the BBC Three series "Clique". Her first major role came when she was cast as Feef Symonds in the Channel 4 spy thriller "Traitors". She is probably best known to audiences as Princess Renfri, appearing alongside Henry Cavill in the fantasy Netflix hit "The Witcher". Appleton will also appear as the main role of Thomasina in the sci-fi film "LOLA", due for release sometime this year.
Playing the lead role of Maggie, who is based on Alderton herself, meant Appleton was under even more pressure as she rehearsed under the watchful eye of the executive producer. Speaking to the BBC on what she has learned from the story, Appleton says it's "how many different kinds of love there are. I think we think that romantic love is the number one thing in our life, when actually there are so many other aspects that are as important." She continues: "It's not just romantic love, it's the love for your friends and your family and the love that you have for yourself."