Experts have stated that physicians should consider prescribing doxylamine (found in Unisom SleepTabs ($12)) in addition to vitamin B6 for treatment of nausea and vomiting of pregnancy because the combination reduces symptoms by 70%.
Although deemed safe by expert panels, the use of doxylamine has been linked to increased risk of a certain birth defect. For this reason, use of this remedy should only be used under a health care provider's supervision.