The former "White Lotus" actor married film producer Andrew Form in June 2022 at Preservation Hall in New Orleans. While the two both posted beautiful images from their fairy-tale day on Instagram, it wasn't until Daddario's September 2022 interview with Women's Health where she really opened up about finding love with Form. "When I met Andrew, we just both knew," she said. "The wedding was wonderful; it felt a bit like an inevitable conclusion. So I feel really at peace."
Prior to her relationship with Form, Daddario and Zac Efron sparked dating rumours after starring alongside each other in the 2017 remake of "Baywatch." However, the two shut down the speculation multiple times, with Daddario telling E! News, "We work together closely; he's my love interest in the film. I understand why people would go crazy over something like that, but Zac and I are very good friends."