A Wrinkle in Time by Madeleine L'Engle What it's about: Fourteen-year-old Meg Murry's father goes missing after working on a government project, setting off Meg's fantastical journey through space and time. Who's starring: Ava DuVernay will direct the adaptation, and the three Mrs. have been cast: Reese Witherspoon will play Mrs. Whatsit, Mindy Kaling will play Mrs. Who, and Oprah Winfrey will play Mrs. Which. See the whole cast here. Watch the trailer for A Wrinkle in Time. Release date: March 9, 2018 Image Source: Everett Collection