Callie's "You Don't Destroy the Person You Love" Speech
Episode: Season 4, Episode 4
What happens: Callie confronts a late patient's boyfriend, who coaxed his girlfriend into dieting and training so that she would lose weight. He tells Callie that he loved his girlfriend, but Callie, who is seething after George confesses to cheating on her with Izzie, lectures that you don't destroy the person you love.