The original cast of "Mean Girls" is pretty iconic, but it turns out that the Plastics almost had a different star in their midst. In a 22 Feb. interview with Vanity Fair, Amanda Seyfried — who played Karen Smith in the classic movie — revealed that the part almost went to none other than Blake Lively.
"I'd flown out to LA for the first time with my mother. It was very exciting," Seyfried said of her audition. Initially, Seyfried had been aiming for the part of Regina George. "I met Lacey Chabert for the first time, and Lindsay Lohan was in the room, and Blake Lively was playing Karen, and then I was Regina," she said. Eventually, of course, Seyfried was picked for Karen.
Although Lively didn't get the role, she went on to score a main role as a queen bee in "Gossip Girl," which premiered in 2007.