On how they've grown up alongside each other: "I would be doing it a disservice to try to put into words what I've been through with Jensen. We've more than grown up together. We went from single 20-somethings to fathers, husbands, and it's hard to quantify in a few short sentences exactly what all that encompasses."
On why he feels lucky to have Jensen: "I think Ackles and I found a really cool, unique situation where we truly enjoy each other and we enjoy each other's families, and have each other's backs, and after 14 years spending more time with each other than you spend with your wives, your kids, your brothers, your sisters, your mothers, your fathers, you kinda go one way or the other, and we went to the place where we got closer. So we're just pretty lucky."
On why his relationship with Jensen is unique: "One of the great things that I've gotten from this show is such a great friend that knows me so well, but also somebody that I can work with on a level that I've never worked with anybody else in my life. So we understand that it's pretty rare and may or may not ever happen again, but we're proud of what we created and we're proud of the people that helped us get here."