Who Has Alex Karev Dated on Grey's Anatomy?
Your Comprehensive Guide to Alex's Romances on Grey's Anatomy
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Yeah, Callie and Alex were a thing for a very hot and steamy second. We don't learn about their little rendezvous until late in the series, though, when on Lecture Day (season six), the ortho surgeon talks about a major reconstruction surgery that she did with Alex. Only Arizona picks up on what happened between them during Callie's speech.