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Season 2, Episode 4: "Deny, Deny, Deny"

Cristina recovers from an ectopic pregnancy, which leads to her hospitalization. While the episode has some levity with hilarious moments (see Oh's "Somebody sedate me" line), it also heightens the drama in the series by exploring Cristina's relationships with her family, friends, and boyfriend as she desperately wishes to go back to work. Somehow, even after losing "a fallopian tube, a baby, and a boyfriend all in one day," she still has the emotional energy to help Meredith with her McDreamy problems.

Image Source: ABC via Giphy