One of two surviving Targaryen royal children, Daenerys fled Westeros as a child along with her older brother Viserys. As she grew older, Viserys schemed to return to Westeros and reclaim the Iron Throne for himself, marrying Daenerys to Khal Drogo, a Dothraki warlord, in hopes of securing an alliance. Instead, Daenerys comes into her own, and Viserys is killed for attempting to attack her. Over several years, she frees slaves, builds alliances, and puts together an enormous force to return to Westeros and claim the throne. Near the end of her quest, she meets Jon Snow, a bastard son of Ned Stark who turns out to actually be her nephew, Aegon Targaryen, and the true Targaryen heir to the throne.
After having a meltdown during her brutal invasion of King's Landing, Daenerys finally reaches the Iron Throne, but Jon kills her before she can sit on it. Her body is flown away by her surviving dragon, Drogon, and never seen again. With her death and Jon's exile, the Targaryen line is officially extinct.