With regard to the renal system, prostaglandins sure come in handy, because they help regulate blood flow to the kidneys. However, “when there are abnormal amounts of prostaglandins, the renal blood vessels constrict, leading to decreased blood flow and increased pressures,” says Dr. Linder. This can cause acute renal failure in more serious cases.
What’s more, altered blood flow to the kidney can change the way the body eliminates electrolytes, so you might notice imbalanced levels of potassium and sodium, which can throw your body out of whack, he says. That means you might be especially dehydrated or you might hold some extra water weight.