Popsugar Health & Fitness Health Breast Cancer Risk Factors The 13 Biggest Risk Factors For Breast Cancer — 5 of Which You Can Change 1 October 2019 by Christina Stiehl View On One Page Photo 4 of 13 ADVERTISEMENT () Start Slideshow Share This Link Copy ← Use Arrow Keys → 4 You Can't Change: Genetic Mutations Inherited gene mutations, such as the BRCA1 and BRCA2 genes, lead to a higher risk of breast and ovarian cancer. Previous Next Start Slideshow HealthHealthy LivingBreast Cancer