What it's about: Fourteen-year-old Meg Murry's father goes missing after working on a government project, setting off Meg's fantastical journey through space and time.
Who's starring:Ava DuVernay will direct the adaptation, and the three Mrs. have been cast: Reese Witherspoon will play Mrs. Whatsit, Mindy Kaling will play Mrs. Who, and Oprah Winfrey will play Mrs. Which. See the whole cast here.