On September 7, 1996, the world changed forever. Heavyweight boxing champion Mike Tyson fought Bruce Seldon and won that night, taking the WBA belt from the former champion. On the same night, rapper Tupac Shakur, whom Tyson was close friends with, attended the fight and planned on going to an after party together with Tyson following his win. Instead, Shakur was shot and killed later that night. One Night in Vegas looks into the friendship between the two, and how that night changed Tyson.